Performance Analysis of Neuralink’s Brain Chip Biocompatible Threads in Signal Acquisition: Efficacy in Motor Function Rehabilitation for Tetraplegic Patients, Era of Brain-Machine Interfaces

Authors

  • Yash Srivastav D.K.R.R Pharmacy College, Amberpur, Sitapur, Uttar Pradesh, India Author
  • Shivani Singh D.K.R.R Pharmacy College, Amberpur, Sitapur, Uttar Pradesh, India Author
  • Vivek Kumar D.K.R.R Pharmacy College, Amberpur, Sitapur, Uttar Pradesh, India Author
  • Stuti Verma D.K.R.R Pharmacy College, Amberpur, Sitapur, Uttar Pradesh, India Author
  • Kamini Prajapati D.K.R.R Pharmacy College, Amberpur, Sitapur, Uttar Pradesh, India Author
  • Saroj Kumar D.K.R.R Pharmacy College, Amberpur, Sitapur, Uttar Pradesh, India Author
  • Anup Kumar Sirbaiya KP Singh Memorial Institute of Pharmacy, Sitapur, Lucknow, Uttar Pradesh 261207 Author

DOI:

https://doi.org/10.64474/3139-1559.Vol2.Issue1.8
Search on Google Scholar

Keywords:

Brain–Machine Interface (BMI), Neuralink, Tetraplegia, Neural Signal Acquisition, Neural Decoding, Neuroprosthetics, Bio-Compatible Neural Threads, Motor Rehabilitation

Abstract

Brain–Machine Interfaces (BMIs) are cutting-edge neuroengineering technologies for direct communication between the human brain and external computational systems in the field of rehabilitation and assistive technologies. The present study measured the performance of the bio-compatible neural threads of Neuralink for signal capture and motor rehabilitation in patients with tetraplegia (four limbs paralysis) from published clinical and technical data secondary to the study between 2019-2025. The analysis was based on the efficiency of neural signal acquisition, implant stability, tissue compatibility, neural decoding accuracy, and the outcomes of rehabilitation. The results showed that the signal quality, neural connectivity preservation and motor rehabilitation efficacy were significantly better than those of traditional BMI systems. The neural stability, biocompatibility and the rehabilitation success demonstrated a strong relationship, which was confirmed by statistical analysis. The study also demonstrated the potential for enhancing brain-to-device communication and neuroprosthetic control with the use of AI-driven neural decoding. These results indicate that the Neuralink invasive BMI architecture could greatly help to restore motor function and enhance the rehabilitation of tetraplegic patients.

References

1. Bandre, P., Daronde, S., Gote, P. M., Yesankar, P., Dhale, T., & Pawar, A. (2025, October). Neuralink: Revolutionizing Brain–Computer Interfaces for Healthcare and Human–AI Integration. In 2025 2nd International Conference on Electronic Circuits and Signaling Technologies (ICECST) (pp. 1122-1126). IEEE.

2. Boufidis, D., Garg, R., Angelopoulos, E., Cullen, D. K., & Vitale, F. (2025). Bio-inspired electronics: Soft, biohybrid, and “living” neural interfaces. Nature Communications, 16(1), 1861.

3. Chen, B., Lu, J., Chen, Z., Han, X., Sun, Y., Lin, X., ... & Xie, R. (2025). Long-term implantable flexible neural interfaces for electrophysiological monitoring. Journal of Materials Chemistry C, 13(12), 5951-5980.

4. Firuzi, R., Ahmadyani, H., Abdi, M. F., Naderi, D., Hassan, J., & Bokani, A. (2022). Decoding neural signals with computational models: A systematic review of invasive BMI. arXiv preprint arXiv:2211.03324.

5. Firuzi, R., Bokani, A., Hassan, J., Ahmadyani, H., Abdi, M. F., Naderi, D., & Ebrahimi, D. (2025). Decoding Neural Signals: Invasive BMI Review. In Modern Technologies in Healthcare (pp. 151-211). CRC Press.

6. Gao, X., Wang, Y., Chen, X., Liu, B., & Gao, S. (2025). Brain–computer interface—a brain-in-the-loop communication system. Proceedings of the IEEE.

7. Jadeja, Y., & Dudhat, K. (2025). Advancements in the Brain Chip Technology: Current Landscape and Future Prospects. Analytical and Bioanalytical Electrochemistry, 17(2), 85-134.

8. Kumar, P., Chakraborty, S., & Sahai, N. (2025). Neuroengineering and brain-machine interfaces. In Innovations in Biomedical Engineering (pp. 325-357). Academic Press.

9. Kumar, R., Waisberg, E., Ong, J., & Lee, A. G. (2025). Response to letter to the editor on ‘the potential power of Neuralink–how brain-machine interfaces can revolutionize medicine’. Expert Review of Medical Devices, 22(8), 781-782.

10. Liu, X., Gong, Y., Jiang, Z., Stevens, T., & Li, W. (2024). Flexible high-density microelectrode arrays for closed-loop brain–machine interfaces: a review. Frontiers in Neuroscience, 18, 1348434.

11. Musk, E. (2019). An integrated brain-machine interface platform with thousands of channels. Journal of medical Internet research, 21(10), e16194.

12. Ramaswamy, P. (2022). Prospects of brain–machine interfaces for space system control. Acta Astronautica.

13. Sahu, C. (2025). Neuralink and Its Advantages: Advancements in Brain-Computer Interface Technology. IJSAT-International Journal on Science and Technology, 16(3).

14. Urbaite, G. (2025). Advancements in Neural Implants: A Systematic Review of Neuralink-Enabled Brain-Machine Communication. Luminis Applied Science and Engineering, 2(3), 46-65.

15. Varughese, J. S., Arjun, M., Mishra, S., & Venkatesh, M. P. (2025). Brain-computer Interface on Medical Devices: A Promising Technology with Limitless Possibilities. Applied Drug Research, Clinical Trials and Regulatory Affairs, 11(1), E26673371314770.

df

Downloads

Published

2026-06-06

How to Cite

Srivastav, Y. S., Singh, S. S., Kumar, V. K., Verma, S. V., Prajapati, K. P., Kumar, S. K., & Sirbaiya, A. K. S. (2026). Performance Analysis of Neuralink’s Brain Chip Biocompatible Threads in Signal Acquisition: Efficacy in Motor Function Rehabilitation for Tetraplegic Patients, Era of Brain-Machine Interfaces. Research Journal of Advanced Multidisciplinary Insights (RJAMI), 80-93. https://doi.org/10.64474/3139-1559.Vol2.Issue1.8